Abdel-Latif al-Qaddoumi was born in the village of Jinsafut, located in Qalqilya district, in 1912, studied at the as-Salaheya School in Nablus and then at an-Najah College. He lived in Yafa from 1930 and 1937. In 1938, he engaged in revolutionary action against British colonialism, and accordingly, the British Authorities arrested him and exiled him to Palmyra in Syria. From there, he fled to Baghdad and enrolled at the Military College. In 1940, he returned to Palestine, and in 1945 he married Lamia al-Qaddoumi and settled in Yafa until 1948. Forcibly displaced from there, he returned to his village. He settled later in the town of Shuafat, located in Jerusalem district, and worked in the al-Aqari al-Rabi Bank before he died in 1975.

The Abdel-Latif al-Qaddoumi Collection contains a handwritten diary that includes details of al-Qaddoumi's life from birth to death. It also contains several personal photographs, in addition to notes on some of the political events he lived through. Al-Qaddoumi was unable to finish writing his memoirs, so his son, Walid, wrote the last page in the notebook.